Wednesday, September 18, 2024

Metformin and Brain Aging


Nature news has an interesting piece on this study which examined the impact of metformin on the brain aging of monkeys. Encouraging findings. 

A sample from the news item:

A low-cost diabetes drug slows ageing in male monkeys and is particularly effective at delaying the effects of ageing on the brain, finds a small study that tracked the animals for more than three years1. The results raise the possibility that the widely used medication, metformin, could one day be used to postpone ageing in humans.

Monkeys that received metformin daily showed slower age-associated brain decline than did those not given the drug. Furthermore, their neuronal activity resembled that of monkeys about six years younger (equivalent to around 18 human years) and the animals had enhanced cognition and preserved liver function.

Cheers, 

Colin